Exsil 80 Octyl

C8 Silica Phase for Balanced Reversed-Phase HPLC Separations

Exsil 80 Octyl is a silica-based HPLC stationary phase with an 80 Å pore size and an octyl (C8) bonded surface, designed for balanced reversed-phase separations of small molecules. The medium-length alkyl chain provides moderate hydrophobic retention, enabling faster elution compared to C18 phases while maintaining good resolution and selectivity.

The controlled pore structure and high surface area of Exsil 80 Octyl support high chromatographic efficiency, sharp peak shapes, and reproducible retention behavior. This makes the phase particularly suitable for analytes that are excessively retained on C18 columns or require shorter analysis times.

Exsil 80 Octyl offers balanced retention, high efficiency, and reliable performance, making it a practical choice for fast and reproducible reversed-phase HPLC separations of small molecules.

Key Features:

  • Silica-based HPLC stationary phase with 80 Å pore size

  • Octyl (C8) bonded phase for moderate hydrophobic retention

  • Faster elution compared to C18 with maintained selectivity

  • High efficiency and reproducible chromatographic performance

  • Optimized for small-molecule reversed-phase HPLC

  • Available particle sizes: 3 µm, 5 µm, 10 µm

Typical Applications:

  • Reversed-phase separation of low-molecular-weight pharmaceuticals

  • Analysis of moderately hydrophobic compounds

  • Method development requiring reduced retention strength

  • High-throughput HPLC with shorter run times

  • Food, environmental, and chemical analysis

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 80 Å
Surface Area 220 m²/g
Phase/Modification C8
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 6 %
pH Range 2 to 8

Material Numbers

Phase Material Number
Exsil 80 Octyl, 3 µm 5136481.
Exsil 80 Octyl, 5 µm 5136492.
Exsil 80 Octyl, 10 µm 5136503.
Exsil 80 C1 (TMS) Exsil 80 Hexyl

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info@dr-maisch.com +49 7073 5035 7

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