Exsil 80 SAX

Strong Anion Exchange Silica for Ionic and Polar HPLC Separations

Exsil 80 SAX is a silica-based HPLC stationary phase with an 80 Å pore size and a strong anion exchange (SAX) bonded surface featuring quaternary ammonium functional groups. This stationary phase provides strong ionic interactions with negatively charged analytes, enabling highly selective and reproducible separations of acidic and polar compounds.

The controlled pore structure offers a high surface area, supporting high loading capacity, sharp peak shapes, and excellent chromatographic efficiency for small-molecule separations. Exsil 80 SAX is suitable for isocratic and gradient ion-exchange chromatography and can also be combined with organic modifiers to fine-tune selectivity.

Exsil 80 SAX delivers strong ionic retention, high efficiency, and reliable reproducibility, making it a robust choice for anion-exchange HPLC separations of small molecules.

Key Features:

  • Silica-based HPLC stationary phase with 80 Å pore size

  • Strong anion exchange (SAX) bonded phase

  • High selectivity for acidic and negatively charged analytes

  • High efficiency and reproducible retention behavior

  • Suitable for ion-exchange and mixed-mode HPLC

  • Available particle sizes: 5 µm, 10 µm

Typical Applications:

  • Separation of acidic pharmaceuticals and drug metabolites

  • Analysis of organic acids and acidic intermediates

  • Ion-exchange chromatography of polar small molecules

  • Method development for anionic compounds

  • Pharmaceutical, chemical, food, and environmental analysis

Specifications

Request Product
Particle Sizes
  • 5 µm
  • 10 µm
Pore Size 80 Å
Surface Area 220 m²/g
Phase/Modification SAX
Particle Type
Separation Mode
USP Code

Material Numbers

Phase Material Number
Exsil 80 SAX, 5 µm 5136495.
Exsil 80 SAX, 10 µm 5136505.
Exsil 80 Phenyl Exsil 80 SB-C8

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