Exsil 80 SB-C8

Stable-Bond C8 Silica Phase for Robust Reversed-Phase HPLC

Exsil 80 SB-C8 is a silica-based HPLC stationary phase with an 80 Å pore size and a stable-bond octyl (C8) modification, designed for robust and reproducible reversed-phase separations of small molecules. The stable-bond (SB) technology provides enhanced chemical stability of the bonded phase, resulting in improved column lifetime and reliable performance under demanding chromatographic conditions.

The C8 alkyl chain offers moderate hydrophobic retention, enabling faster elution compared to C18 phases while maintaining good resolution and selectivity. Combined with the controlled pore structure and high surface area, Exsil 80 SB-C8 delivers sharp peak shapes, high efficiency, and excellent batch-to-batch reproducibility.

Exsil 80 SB-C8 provides balanced retention, enhanced stability, and reliable performance, making it a dependable choice for robust small-molecule reversed-phase HPLC separations.

Key Features:

  • Silica-based HPLC stationary phase with 80 Å pore size

  • Stable-bond octyl (C8) bonded phase

  • Enhanced chemical stability and long column lifetime

  • Moderate hydrophobic retention with faster analysis times than C18

  • High efficiency and reproducible chromatographic performance

  • Optimized for small-molecule reversed-phase HPLC

  • Available particle sizes: 3 µm, 5 µm

Typical Applications:

  • Reversed-phase separation of low-molecular-weight pharmaceuticals

  • Analysis of moderately hydrophobic compounds

  • Routine QC and method development requiring robust C8 selectivity

  • High-throughput HPLC with reduced run times

  • Food, environmental, and chemical analysis

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 80 Å
Surface Area 220 m²/g
Phase/Modification C8
Particle Type
Separation Mode
USP Code

Material Numbers

Phase Material Number
Exsil 80 SB-C8, 3 µm 6136943.
Exsil 80 SB-C8, 5 µm 6136861.
Exsil 80 SAX Exsil 80 SB-C18

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