Exsil 80 SCX is a silica-based HPLC stationary phase with an 80 Å pore size and a strong cation exchange (SCX) bonded surface based on sulfonic acid functional groups. This chemistry provides strong ionic interactions with positively charged analytes, enabling highly selective and reproducible separations of basic and cationic compounds.
The controlled pore structure delivers a high surface area, supporting high loading capacity, sharp peak shapes, and excellent chromatographic efficiency for small-molecule applications. Exsil 80 SCX is suitable for isocratic and gradient ion-exchange chromatography and can also be applied in mixed-mode HPLC when combined with organic modifiers.
Exsil 80 SCX provides strong ionic retention, high efficiency, and reliable reproducibility, making it a robust solution for cation-exchange HPLC separations of small molecules.
Silica-based HPLC stationary phase with 80 Å pore size
Strong cation exchange (SCX) bonded phase
High selectivity for basic and positively charged analytes
High efficiency and reproducible retention behavior
Suitable for ion-exchange and mixed-mode HPLC
Available particle sizes: 3 µm, 5 µm, 10 µm
Separation of basic pharmaceuticals and drug metabolites
Analysis of amines and other cationic small molecules
Ion-exchange chromatography of polar compounds
Method development for basic analytes
Pharmaceutical, chemical, food, and environmental analysis
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Surface Area | 220 m²/g |
| Phase/Modification | SCX |
| Particle Type | |
| Separation Mode | |
| USP Code |
| Phase | Material Number |
|---|---|
| Exsil 80 SCX, 3 µm | 5136806. |
| Exsil 80 SCX, 5 µm | 5136496. |
| Exsil 80 SCX, 10 µm | 6136937. |