Exsil 80 Si is a silica-based HPLC stationary phase with an 80 Å pore size and an unmodified silica (Si) surface. The exposed silanol groups provide strong polar surface interactions, including hydrogen bonding and dipole–dipole interactions, making this phase ideally suited for normal-phase chromatography and separations of polar compounds.
The controlled pore structure delivers a high surface area, supporting high chromatographic efficiency, sharp peak shapes, and reproducible retention behavior for small-molecule applications. Exsil 80 Si is widely used where reversed-phase HPLC provides insufficient retention or selectivity and serves as a complementary tool in method development.
Exsil 80 Si delivers reliable polar selectivity, high efficiency, and robust performance, making it a proven choice for normal-phase HPLC separations of small molecules.
Silica-based HPLC stationary phase with 80 Å pore size
Unmodified silica surface with active silanol groups
Strong polar interactions for normal-phase HPLC
High efficiency and reproducible chromatographic performance
Suitable for small-molecule separations and method development
Available particle sizes: 3 µm, 5 µm, 10 µm
Normal-phase separation of polar organic compounds
Resolution of structural and positional isomers
Analysis of lipids, sterols, and natural products
Complementary selectivity to reversed-phase HPLC
Pharmaceutical, chemical, food, and environmental analysis
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Surface Area | 220 m²/g |
| Phase/Modification | Si |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| Carbonload | 0 % |
| Phase | Material Number |
|---|---|
| Exsil 80 Si, 3 µm | 5136458. |
| Exsil 80 Si, 5 µm | 5136487. |
| Exsil 80 Si, 10 µm | 5136501. |