Exsil Avanti Si

High-Purity Bare Silica for Normal-Phase and HILIC HPLC

Exsil Avanti Si is a premium unmodified silica stationary phase designed for high-performance normal-phase chromatography, adsorption chromatography, and HILIC applications in both HPLC and UHPLC systems. The highly active polar silica surface enables strong interactions through hydrogen bonding and dipole-dipole forces, making it ideal for the separation of polar and structurally related compounds.

The advanced Exsil Avanti high-purity spherical silica platform ensures uniform particle morphology, excellent mechanical strength, and reproducible chromatographic performance. The optimized pore structure supports efficient mass transfer, delivering high column efficiency, sharp peak shapes, and consistent retention behavior — even under high-pressure UHPLC conditions. Exsil Avanti Si is particularly suited for the separation of polar organic molecules, isomers, carbohydrates, lipids, and adsorption-driven analytes. In HILIC mode, the hydrophilic surface promotes stable retention of highly polar compounds under aqueous-organic mobile phase conditions. Its versatility makes it a reliable choice for pharmaceutical, chemical, environmental, and food safety laboratories.

Exsil Avanti Si combines the selectivity of high-purity bare silica with advanced particle technology — delivering precise, reproducible, and high-efficiency separations for polar and adsorption-based chromatographic applications.

Key Features

  • High-purity bare silica (Si) stationary phase

  • Ideal for normal-phase and HILIC chromatography

  • Strong polar surface interactions for selective separations

  • High efficiency with excellent peak symmetry

  • Robust spherical silica particles for long column lifetime

  • Compatible with adsorption-based and hydrophilic workflows

Typical Applications

  • Normal-phase separation of polar compounds

  • HILIC analysis of highly hydrophilic analytes

  • Isomer and structural variant separations

  • Carbohydrate and lipid analysis

  • Method development in adsorption chromatography

Specifications

Request Product
Particle Sizes
  • 1.5 µm
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 130 Å
Surface Area 195 m²/g
Phase/Modification Si
Particle Type
Separation Mode
USP Code
Endcapping No
Carbonload 0 %
pH Range 2 - 8

Material Numbers

Phase Material Number
Exsil Avanti Si, 1.5 µm 5136621.
Exsil Avanti Si, 3 µm 5136622.
Exsil Avanti Si, 5 µm 5136623.
Exsil Avanti Si, 10 µm 6136934.
Exsil Avanti SCX

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us