Exsil Avanti SCX is a high-performance strong cation exchange (SCX) silica stationary phase designed for efficient and reproducible ion-exchange chromatography in HPLC and UHPLC systems. Functionalized with sulfonic acid groups, this phase provides stable and powerful electrostatic interactions for the retention of positively charged analytes across a broad pH range.
The permanently charged sulfonic acid functionality ensures consistent cation-exchange capacity, making Exsil Avanti SCX ideal for the separation of amines, basic pharmaceuticals, peptides, alkaloids, and other cationic compounds. Its optimized surface chemistry minimizes unwanted secondary interactions, delivering sharp peak symmetry and predictable retention behavior. Built on the advanced Exsil Avanti high-purity spherical silica platform, the phase offers excellent mechanical strength, uniform particle morphology, and long column lifetime. It performs reliably under aqueous buffer conditions and supports gradient elution using salt concentration or pH adjustment — providing flexibility for analytical, preparative, and method development applications.
Exsil Avanti SCX combines strong, stable cation-exchange chemistry with high-efficiency silica technology — delivering precise, reproducible, and high-resolution ion-exchange separations for modern analytical laboratories.
Strong cation exchange (SCX) functionality with sulfonic acid groups
High retention capacity for positively charged analytes
Stable performance over a wide pH range
High efficiency and reproducible chromatographic results
Robust spherical silica for UHPLC and high-pressure operation
Compatible with aqueous buffers and salt gradients
Ion-exchange separation of basic pharmaceuticals and APIs
Analysis of amines, peptides, and alkaloids
Impurity profiling and metabolite analysis
Biochemical and environmental testing
Method development in cation-exchange chromatography
| Particle Size |
|
|---|---|
| Pore Size | 130 Å |
| Surface Area | 195 m²/g |
| Phase/Modification | SCX |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | No |
| Carbonload | 5 % |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| Exsil Avanti SCX, 5 µm | 5136637. |