Gold-Turbo Amid-C12 is a reversed-phase HPLC column based on fully porous, high-purity silica, bonded with dodecyl (C12) chains containing a polar amide group. This polar-embedded phase combines hydrophobic retention with enhanced selectivity for polar and ionizable analytes, while also reducing silanol interactions. It is ideal for separating compounds that show peak tailing or insufficient retention on standard C18 columns, especially under aqueous or mixed-mode conditions.
C12 bonded phase with polar amide embedding
Dual retention mechanism: hydrophobic + polar interactions
Excellent peak shape for basic and polar compounds
Suitable for 100% aqueous mobile phases
Available in 3 µm and 5 µm particle sizes
Polar drug substances and metabolites
Compounds with poor retention or peak shape on C18
Aqueous reversed-phase separations and pH-sensitive analytes
Complex matrix separations requiring alternative selectivity
Gold-Turbo Amid-C12 offers a unique combination of retention and selectivity – the ideal column for challenging reversed-phase separations involving polar and ionizable compounds.
| Particle Size |
|
|---|---|
| Phase/Modification | AMID-C12 |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | endc. |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Gold-Turbo Amid-C12, 1.5 µm | g22.a12. |