Gold-Turbo ESM C18 is a reversed-phase HPLC column based on fully porous, high-purity silica, bonded with C18 chains containing embedded polar groups (ESM: Embedded Selectivity Modifier). This design enables hydrophobic retention typical of C18 phases, while the embedded polar functionality improves peak shape for basic compounds, enhances selectivity for polar analytes, and allows for operation under highly aqueous conditions without phase collapse.
Gold-Turbo ESM C18 is particularly suitable for challenging analytes and method development where standard C18 columns offer insufficient retention or poor symmetry.
C18 bonded phase with embedded polar groups – USP L1
Improved peak shape for basic and polar compounds
Stable performance in 100% aqueous mobile phases
Dual retention mode: hydrophobic and polar selectivity
Available in 3 µm and 5 µm particle sizes
Basic drug substances, metabolites, and degradation products
Highly polar or early-eluting analytes
Aqueous reversed-phase separations
Method development requiring alternative selectivity profiles
Gold-Turbo ESM C18 combines robust C18 performance with enhanced polar interaction – an advanced column for modern reversed-phase separations.
| Particle Size |
|
|---|---|
| Phase/Modification | ESM C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | endc. |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Gold-Turbo ESM C18, 1.5 µm | g015.9e. |