Grom Sapphire 110 C4 is a silica-based HPLC column with a butyl (C4) bonded phase on high-purity 110 Å silica. Compared to longer-chain alkyl phases such as C18 or C8, the shorter C4 chains provide reduced hydrophobic retention, enabling faster elution and improved resolution for moderately hydrophobic or amphiphilic compounds.
The 110 Å pore size offers an optimal balance between surface area and accessibility, making Sapphire 110 C4 particularly suited for peptides, small biomolecules, and moderately hydrophobic analytes. Its robust bonding chemistry ensures sharp peak shapes, reproducibility, and long operational lifetime.
Grom Sapphire 110 C4 provides reliable performance with reduced hydrophobic selectivity – the dependable choice for laboratories analyzing peptides, small biomolecules, and moderately hydrophobic analytes in HPLC.
High-purity silica stationary phase with butyl (C4) bonded chemistry
110 Å pore size for small molecules and peptides
Reduced hydrophobic retention compared to C18 or C8 phases
Robust bonding ensures reproducibility and long column lifetime
Available particle size: 5 µm
Peptide and small protein analysis with controlled retention
Pharmaceutical impurity profiling of moderately hydrophobic drugs
Biochemical testing of amphiphilic molecules and metabolites
Method development requiring reduced hydrophobic retention
| Particle Size |
|
|---|---|
| Pore Size | 110 Å |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| Grom Sapphire 110 C4, 5 µm | GSBUS0511. |