Grom Sapphire 110 C8 is a silica-based HPLC column with an octyl (C8) bonded phase on high-purity 110 Å silica. Compared to C18 phases, the shorter C8 chains provide reduced hydrophobic retention, allowing faster elution and improved resolution for moderately hydrophobic analytes.
The 110 Å pore size provides excellent mass transfer properties, ensuring sharp peak shapes and reproducibility for small to medium-sized molecules. With robust bonding chemistry, Sapphire 110 C8 offers consistent performance and long operational lifetimes under routine and demanding chromatographic conditions.
Grom Sapphire 110 C8 provides reliable performance and balanced retention – the versatile choice for laboratories performing reversed-phase HPLC separations of moderately hydrophobic analytes.
High-purity silica stationary phase with octyl (C8) bonded chemistry
110 Å pore size optimized for small to medium-sized molecules
Balanced hydrophobic retention with faster elution than C18 phases
Robust bonding ensures reproducibility and long column lifetime
Available particle sizes: 3 µm, 5 µm
Pharmaceutical impurity profiling and stability testing
Biochemical analysis of moderately hydrophobic drugs and metabolites
Food and beverage testing for additives, preservatives, and contaminants
Environmental monitoring of hydrophobic organic pollutants
Method development requiring balanced hydrophobic selectivity
| Particle Sizes |
|
|---|---|
| Pore Size | 110 Å |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Grom Sapphire 110 C8, 3 µm | GSOCS0311. |
| Grom Sapphire 110 C8, 5 µm | GSOCS0511. |