Grom Sapphire 110 Si

High-Purity Bare Silica Column for Normal-Phase Chromatography and Adsorption Separations

GromSil Sapphire 110 Si is a normal-phase HPLC column from Dr. Maisch HPLC GmbH, based on ultra-high-purity, fully porous silica with a 110 Å pore size and a highly uniform surface. This unmodified silica phase provides strong polar retention through active silanol groups and is ideally suited for adsorption chromatography, the separation of polar analytes, and sample loading in preparative LC.

The intermediate pore size offers optimal retention and mass transfer for small to medium-sized polar compounds, with excellent mechanical stability and reproducible retention behavior.

With its high-purity silica and robust retention profile, GromSil Sapphire 110 Si from Dr. Maisch HPLC GmbH is a dependable choice for laboratories focused on normal-phase and polar compound separations.

Key Features:

  • Bare silica phase – USP L3 classification

  • Ultra-pure silica with 110 Å pore size and high surface activity

  • Strong silanol interaction for polar retention

  • Excellent reproducibility and suitability for non-aqueous eluents

  • Available in 5 µm and 10 µm particle sizes

Typical Applications:

  • Normal-phase LC of polar small molecules, acids, alcohols, and isomers

  • Adsorption-based separations and dry-loading workflows

  • Method development with orthogonal selectivity to reversed-phase LC

  • Preparative or analytical use in pharmaceutical and chemical research

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 110 Å
Particle Type
Separation Modes
USP Code
pH Range 2 - 8

Material Number

Phase Material Number
Grom Sapphire 110 Si, 5 µm GSNPS0511.
Grom Sapphire 110 C18

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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