Grom Sapphire 110 C18

Standard Reversed-Phase HPLC Column for Robust Small Molecule Analysis

Grom Sapphire 110 C18 is a silica-based HPLC column with an octadecyl (C18) bonded phase on high-purity 110 Å silica. As the most widely used stationary phase, C18 delivers strong hydrophobic retention, reproducible selectivity, and reliable performance, making it ideal for routine and advanced reversed-phase separations.

The 110 Å pore size provides an excellent balance of surface area and accessibility, ensuring high efficiency, sharp peak shapes, and consistent results for small to medium-sized molecules. With robust bonding chemistry, Sapphire 110 C18 ensures long column lifetimes and reproducibility under routine and demanding analytical conditions.

Grom Sapphire 110 C18 delivers proven C18 performance with reproducibility and robustness – the reliable choice for laboratories conducting reversed-phase HPLC separations of small to medium-sized molecules.

Key Features:

  • High-purity silica stationary phase with octadecyl (C18) bonded chemistry

  • 110 Å pore size optimized for small to medium-sized molecules

  • Strong hydrophobic retention with reproducible selectivity

  • Robust bonding ensures long operational lifetime

  • Available particle sizes: 3 µm, 5 µm, 10 µm

Typical Applications:

  • Pharmaceutical impurity profiling and stability-indicating assays

  • Biochemical analysis of hydrophobic drugs and metabolites

  • Food and beverage testing for preservatives, additives, and contaminants

  • Environmental monitoring of organic pollutants

  • Method development requiring robust and reproducible C18 selectivity

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 110 Å
Particle Type
Separation Mode
USP Code
pH Range 2 to 8

Material Numbers

Phase Material Number
Grom Sapphire 110 C18, 3 µm GSODS0311.
Grom Sapphire 110 C18, 5 µm GSODS0511.
Grom Sapphire 110 C18, 10 µm GSODS1011.
Grom Sapphire 110 C8 Grom Sapphire 110 Si

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us