Grom Sapphire 65 C8

Medium Hydrophobicity HPLC Column for Versatile Small Molecule Analysis

Grom Sapphire 65 C8 is a silica-based HPLC column with an octyl (C8) bonded phase, built on high-purity 65 Å silica. Compared to C18 phases, the shorter C8 chains provide reduced hydrophobic retention, enabling faster elution and improved peak resolution for moderately hydrophobic analytes.

With its optimized surface chemistry, Sapphire 65 C8 ensures reproducible performance, sharp peak shapes, and long column lifetimes. It is particularly suitable for pharmaceutical quality control, biochemical analysis, and routine testing of complex mixtures where balanced hydrophobicity is required.

Grom Sapphire 65 C8 provides reliable performance and balanced hydrophobic selectivity – the dependable choice for laboratories requiring efficient small-molecule separations in HPLC.

Key Features:

  • High-purity silica stationary phase with octyl (C8) bonded chemistry

  • 65 Å pore size optimized for small molecule separations

  • Balanced hydrophobic retention with faster elution than C18 phases

  • Robust bonding ensures reproducibility and long lifetime

  • Available particle sizes: 3 µm, 5 µm

Typical Applications:

  • Pharmaceutical impurity profiling and stability testing

  • Biochemical analysis of moderately hydrophobic drugs and metabolites

  • Food and beverage testing for organic additives and contaminants

  • Method development requiring reduced hydrophobic retention compared to C18

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 65 Å
Particle Type
Separation Mode
USP Code
pH Range 2 to 8

Material Numbers

Phase Material Number
Grom Sapphire 65 C8, 3 µm GSOCS0307.
Grom Sapphire 65 C8, 5 µm GSOCS0507.
Grom Sapphire 65 C18

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