Grom Sapphire 65 C18

Standard Reversed-Phase HPLC Column for Robust Small Molecule Analysis

Grom Sapphire 65 C18 is a silica-based HPLC column with an octadecyl (C18) bonded phase on high-purity 65 Å silica. As the most widely used stationary phase, C18 provides strong hydrophobic retention and excellent reproducibility, making this column ideal for routine and advanced separations of small molecules.

The 65 Å pore size offers high surface area and optimized mass transfer, ensuring sharp peak shapes, high efficiency, and consistent results. With robust bonding chemistry, Sapphire 65 C18 delivers long operational lifetimes under routine and demanding chromatographic conditions.

Grom Sapphire 65 C18 delivers proven C18 performance with robustness and reproducibility – the trusted choice for laboratories conducting reversed-phase HPLC separations of small molecules.

Key Features:

  • High-purity silica stationary phase with octadecyl (C18) bonded chemistry

  • 65 Å pore size optimized for small molecule separations

  • Strong hydrophobic retention with reproducible selectivity

  • Robust bonding ensures long column lifetime and consistent performance

  • Available particle sizes: 3 µm, 5 µm

Typical Applications:

  • Pharmaceutical impurity profiling and stability-indicating assays

  • Biochemical analysis of hydrophobic drugs and metabolites

  • Food and beverage testing for additives, contaminants, and preservatives

  • Environmental monitoring of organic pollutants

  • Method development requiring robust C18 selectivity

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 65 Å
Particle Type
Separation Mode
USP Code
pH Range 2 to 8

Material Numbers

Phase Material Number
Grom Sapphire 65 C18, 3 µm GSODS0307.
Grom Sapphire 65 C18, 5 µm GSODS0507.
Grom Sapphire 65 C8 Grom Sapphire 65 Si

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