Grom Sapphire 65 Si

High-Purity Bare Silica Column for Normal-Phase and Adsorption Chromatography

GromSil Sapphire 65 Si is a normal-phase HPLC column from Dr. Maisch HPLC GmbH, packed with ultra-high-purity, fully porous silica featuring a 65 Å pore size and a highly uniform particle structure. Designed for strong polar retention through active silanol groups, this unmodified phase is ideal for classical normal-phase chromatography, adsorption-based separations, and dry-loading applications in preparative LC.

Its optimized surface activity ensures reproducible retention and peak shape, even in non-aqueous mobile phases.

Thanks to its high-purity surface and robust retention behavior, GromSil Sapphire 65 Si from Dr. Maisch HPLC GmbH is a reliable solution for laboratories performing normal-phase and adsorption chromatography on polar analytes.

Key Features:

  • Bare silica phase – USP L3 classification

  • Ultra-pure silica with 65 Å pore size and high surface activity

  • Strong polar retention via silanol interactions

  • Excellent batch-to-batch reproducibility and mechanical stability

  • Available in 5 µm and 10 µm particle sizes

Typical Applications:

  • Separation of polar compounds, alcohols, acids, and isomers

  • Normal-phase chromatography with hexane, heptane, or ethyl acetate

  • Sample pre-concentration and dry-loading in preparative workflows

  • Orthogonal selectivity to reversed-phase and HILIC methods

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 65 Å
Particle Type
Separation Modes
USP Code
pH Range 2 to 8

Material Number

Phase Material Number
Grom Sapphire 65 Si, 5 µm GSNPS0507.
Grom Sapphire 65 C18

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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