GromSil 200 Butyl-1 ST is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, packed with fully porous, high-purity silica featuring a 200 Å pore size and bonded with butyl (C4) ligands. The short alkyl chain provides weak hydrophobic interaction, which allows faster elution of strongly retained or bulky analytes such as large peptides, hydrophobic compounds, and lipophilic drug candidates.
Its wide-pore architecture ensures efficient mass transfer and accessibility for high-molecular-weight substances, while standard endcapping (ST) minimizes silanol activity to improve peak shape and reproducibility.
With its combination of wide pores and mild hydrophobicity, GromSil 200 Butyl-1 ST from Dr. Maisch HPLC GmbH is ideal for fast and reliable separations of high-molecular-weight or lipophilic analytes in reversed-phase HPLC.
Butyl (C4) bonded reversed-phase phase with standard endcapping – USP L26
Fully porous silica with 200 Å pore size for large or hydrophobic analytes
Lower retention strength for faster separations
Improved peak symmetry and reproducibility for basic compounds
Available in 3 µm, 5 µm, and 10 µm particle sizes
Hydrophobic peptides, lipophilic drugs, and protein fragments
Fast reversed-phase separations with sharp peaks
Method development for challenging, strongly retained compounds
LC-MS and UV workflows in pharmaceutical and bioanalytical settings
| Particle Sizes |
|
|---|---|
| Pore Size | 200 Å |
| Phase/Modification | C4 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 200 Butyl-1 ST, 3 µm | GSBU10320. |
| GromSil 200 Butyl-1 ST, 5 µm | GSBU10520. |
| GromSil 200 Butyl-1 ST, 10 µm | GSBU11020. |