GromSil 200 Diol

Wide-Pore Diol Phase for Polar Compound Separation and HILIC-Like Chromatography

GromSil 200 Diol is a polar HPLC column from Dr. Maisch HPLC GmbH, based on high-purity, fully porous silica with a 200 Å pore size and bonded with diol (–CH₂OH–CH₂OH) functional groups. The wide-pore structure enables efficient mass transfer and analyte accessibility, making it suitable for separating larger polar compounds such as glycopeptides, oligosaccharides, and hydrophilic biomolecules.

This phase is designed for normal-phase and HILIC-like applications, offering strong dipole and hydrogen-bonding interactions with low surface activity for improved peak shape.

With its broad pore structure and polar selectivity, GromSil 200 Diol from Dr. Maisch HPLC GmbH is ideal for laboratories seeking robust normal-phase or HILIC-style separations of large or hydrophilic compounds.

Key Features:

  • Diol-modified polar phase – comparable to USP L20

  • Fully porous silica with 200 Å pore size for large polar molecules

  • Excellent selectivity for hydroxyl-rich and hydrophilic analytes

  • Suitable for normal-phase and aqueous-organic HILIC conditions

  • Available in 5 µm and 10 µm particle sizes

Typical Applications:

  • Oligosaccharides, glycopeptides, and sugar derivatives

  • Polar biomolecules and small hydrophilic pharmaceuticals

  • HILIC-like separations with acetonitrile-rich eluents

  • Method development with polar interaction mechanisms

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 200 Å
Phase/Modification Diol
Particle Type
Separation Modes
USP Code
pH Range 2 - 8

Material Number

Phase Material Number
GromSil 200 Diol, 5 µm GSOH10520.
GromSil 200 Butyl-1 ST GromSil 200 ODS-4 HE

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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