GromSil 300 Amino-4 PR is a polar HPLC column from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with a 300 Å pore size and bonded with primary amino (–NH₂) functional groups. This wide-pore stationary phase is specifically designed for the normal-phase or HILIC-like separation of larger polar compounds, including oligosaccharides, glycopeptides, and hydrophilic biomolecules.
Its large pore structure ensures efficient mass transfer and analyte accessibility, while the amino functionality provides dipole and hydrogen bonding interactions with enhanced retention for polar analytes.
Combining wide-pore accessibility with polar selectivity, GromSil 300 Amino-4 PR from Dr. Maisch HPLC GmbH is an excellent choice for laboratories working with large or highly polar analytes in bioanalytical and pharmaceutical separations.
Aminopropyl (NH₂) bonded normal-phase/HILIC phase – USP L8
Fully porous silica with 300 Å pore size for large hydrophilic compounds
Strong polar retention and weak anion exchange behavior
Suitable for HILIC, normal-phase, and polar retention mechanisms
Available in 5 µm and 10 µm particle sizes
Separation of oligosaccharides, polyols, and glycopeptides
Normal-phase LC of polar biomolecules and sugar derivatives
HILIC-like applications using acetonitrile-rich eluents
Method development for hydrophilic or polar large molecules
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Phase/Modification | NH2 |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 300 Amino-4 PR, 3 µm | GSNH40330. |
| GromSil 300 Amino-4 PR, 7 µm | GSNH40730. |