GromSil 80 Octyl-4 FE is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with an 80 Å pore size and bonded with octyl (C8) ligands. The fully endcapped (FE) surface minimizes residual silanol activity, resulting in excellent peak symmetry and reproducibility—especially for basic and ionizable analytes.
With moderate hydrophobic retention, this C8 phase provides shorter run times compared to C18 columns while maintaining strong selectivity and performance. It is ideal for pharmaceutical, chemical, and environmental applications requiring high column efficiency and robust method reproducibility.
Thanks to its optimal balance of retention strength and peak performance, GromSil 80 Octyl-4 FE from Dr. Maisch HPLC GmbH is an excellent choice for reliable and reproducible reversed-phase separations in analytical laboratories.
Octyl (C8) bonded reversed-phase phase with full endcapping – USP L7
Fully porous silica with 80 Å pore size
Excellent peak shape and retention for basic and mid-polar analytes
Moderate hydrophobic interaction for shorter analysis times
Available in 3 µm, 5 µm, and 10 µm particle sizes
Pharmaceuticals, intermediates, and related substances
Method development requiring improved peak shape for basic compounds
LC-MS and UV detection in reversed-phase workflows
Routine quality control and impurity profiling
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 80 Octyl-4 FE, 3 µm | GSOC40308. |
| GromSil 80 Octyl-4 FE, 5 µm | GSOC40508. |