GromSil 80 ODS-1 PE is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with an 80 Å pore size and bonded with octadecyl (C18) ligands. The phase is partially endcapped (PE), allowing a portion of residual silanol groups to remain accessible. This results in a balanced retention profile with both hydrophobic and polar interaction characteristics.
Such a configuration is especially useful for the separation of basic, polar, or weakly retained compounds, and provides complementary selectivity to fully endcapped C18 phases.
Offering a distinct retention mechanism and robust chromatographic performance, GromSil 80 ODS-1 PE from Dr. Maisch HPLC GmbH is a versatile choice for reversed-phase separations requiring both hydrophobic and polar selectivity.
Octadecyl (C18) bonded reversed-phase phase with partial endcapping – USP L1
Fully porous silica with 80 Å pore size
Moderate silanol activity for enhanced polar selectivity
Suitable for method development and orthogonal separations
Available in 3 µm, 5 µm, and 10 µm particle sizes
Basic pharmaceuticals, polar small molecules, and isomers
Selectivity screening and reversed-phase method development
LC-MS and UV detection with aqueous-organic eluents
General-purpose analysis in pharmaceutical and chemical R&D
| Particle Sizes |
|
|---|---|
| Pore Size | 80 Å |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil 80 ODS-1 PE, 3 µm | GSOD10308. |
| GromSil 80 ODS-1 PE, 5 µm | GSOD10508. |