Macrosphere 300 SAX is a silica-based strong anion exchange phase designed for the separation and purification of negatively charged biomolecules such as nucleotides, acidic proteins, and peptides. The phase is built on high-purity spherical silica with a 300 Å pore size, providing excellent accessibility for large biomolecules and efficient mass transfer.
Equipped with quaternary ammonium functional groups, Macrosphere 300 SAX offers high ion exchange capacity, strong electrostatic interactions, and outstanding reproducibility under a wide range of buffer conditions. The large-pore silica support ensures robust performance in both analytical and preparative ion exchange chromatography, making it ideal for biopharmaceutical and biochemical applications.
Macrosphere 300 SAX delivers strong anion exchange performance with the accessibility of a large-pore silica support – the reliable choice for high-resolution separation of negatively charged biomolecules.
Silica-based strong anion exchange (SAX) phase with 300 Å pore size
Optimized for acidic and negatively charged biomolecules
High ion exchange capacity and reproducibility
Excellent mechanical stability and long column lifetime
Suitable for analytical and preparative chromatography
Available particle size: 5 µm
Separation and purification of nucleotides, acidic peptides, and proteins
Biopharmaceutical process development and quality control
Method optimization for anion exchange chromatography
| Particle Size |
|
|---|---|
| Pore Size | 300 Å |
| Phase/Modification | SAX |
| Particle Type | |
| Separation Mode | |
| USP Code |
| Phase | Material Number |
|---|---|
| Macrosphere 300 SAX, 5 µm | 5207006 |