Macrosphere 300 SCX is a silica-based strong cation exchange phase functionalized with sulfonic acid groups, developed for the separation of positively charged biomolecules such as basic peptides, proteins, and other macromolecules. The 300 Å pore structure ensures optimal diffusion and mass transfer, enabling efficient separations of high-molecular-weight compounds.
With its strong cation exchange capacity and high mechanical stability, Macrosphere 300 SCX provides consistent performance across a wide range of buffer compositions and pH values. Its robust silica backbone supports reproducible results and long operational lifetime, making it a dependable choice for biotechnological and pharmaceutical laboratories.
Macrosphere 300 SCX combines strong cation exchange functionality with the reliability of a large-pore silica matrix – the trusted solution for reproducible separations of positively charged biomolecules.
Silica-based strong cation exchange (SCX) phase with 300 Å pore size
High binding capacity for positively charged biomolecules
Strong electrostatic interactions for excellent resolution
Robust mechanical and chemical stability
Suitable for analytical and preparative workflows
Available particle size: 5 µm
Separation and purification of basic peptides and proteins
Biopharmaceutical purification and process optimization
Method development for strong cation exchange chromatography
| Particle Size |
|
|---|---|
| Pore Size | 300 Å |
| Phase/Modification | SCX |
| Particle Type | |
| Separation Mode | |
| USP Code |
| Phase | Material Number |
|---|---|
| Macrosphere 300 SCX, 5 µm | 5207007 |