Macrosphere 300 WCX is a silica-based weak cation exchange phase designed for the selective separation of positively charged biomolecules under milder buffer and pH conditions. The phase is built on high-purity spherical silica with a 300 Å pore size, offering excellent pore accessibility and diffusion characteristics for large biomolecules such as peptides and proteins.
Functionalized with weakly acidic carboxylic groups, Macrosphere 300 WCX provides moderate ion exchange strength and fine-tuned selectivity, allowing gentle separations of pH-sensitive compounds or biomolecules prone to denaturation. The robust silica support ensures reproducibility, stability, and long lifetime, even under varying chromatographic conditions.
Macrosphere 300 WCX offers mild and controlled ion exchange selectivity on a stable silica matrix – the ideal choice for reproducible and gentle separation of positively charged biomolecules.
Silica-based weak cation exchange (WCX) phase with 300 Å pore size
Gentle ion exchange interactions for pH-sensitive biomolecules
Fine selectivity control through adjustable buffer and pH conditions
High mechanical and chemical stability
Suitable for analytical and preparative separations
Available particle size: 7 µm
Separation of peptides and proteins under mild chromatographic conditions
Purification of pH-sensitive or labile biomolecules
Biopharmaceutical and biochemical research requiring selective cation exchange
| Particle Size |
|
|---|---|
| Pore Size | 300 Å |
| Phase/Modification | WCX |
| Particle Type | |
| Separation Mode | |
| USP Code |
| Phase | Material Number |
|---|---|
| Macrosphere 300 WCX, 7 µm | 5207014 |