ReproSil Mixed-Mode Amino-C8

Dual-Function HPLC Column for Balanced Polar and Hydrophobic Separations

ReproSil Mixed-Mode Amino-C8 from Dr. Maisch HPLC GmbH is a high-purity silica-based HPLC column with a mixed-mode stationary phase combining aminopropyl functionality and octyl bonding. This hybrid chemistry provides polar interaction capability alongside moderate hydrophobic retention, enabling versatile separations for analytes with a wide range of polarities. The medium-chain C8 phase offers faster elution than C18 while retaining sufficient hydrophobic selectivity, making this column ideal for method development where balanced retention and dual-mode selectivity are required.

ReproSil Mixed-Mode Amino-C8 columns from Dr. Maisch HPLC GmbH provide balanced retention with dual selectivity – the flexible choice for complex mixture HPLC separations.

Key Features:

  • Fully porous, ultra-pure silica with dual amino and C8 bonding

  • Mixed-mode retention: polar interactions plus moderate hydrophobicity

  • Balanced selectivity for polar and non-polar analytes

  • High efficiency and reproducibility for small-molecule separations

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 3 µm and 5 µm particle sizes

Typical Applications:

  • Separation of mixed-polarity compound classes

  • Pharmaceutical and metabolite profiling

  • Method development requiring intermediate hydrophobic retention

  • Food, environmental, and natural product analysis

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 100 Å
Surface Area 200 m²/g
Phase/Modification C8-NH2
Particle Type
Separation Modes
USP Codes
Endcapping No
Carbonload 11 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil Mixed-Mode Amino-C8, 3 µm r13.8a.
ReproSil Mixed-Mode Amino-C8, 5 µm r15.8a.
ReproSil Mixed-Mode Amino-C18

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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