ReproSil Mixed-Mode Amino-C18 from Dr. Maisch HPLC GmbH is a high-purity silica-based HPLC column featuring a mixed-mode stationary phase that combines aminopropyl functionality with octadecyl bonding. This dual chemistry enables reversed-phase and polar interaction mechanisms within a single column, offering unique selectivity for complex mixtures containing both hydrophilic and hydrophobic compounds. The combination of polar amino groups and hydrophobic C18 chains allows analysts to fine-tune separations, making this column an excellent choice for method development and challenging applications requiring multiple interaction modes.
ReproSil Mixed-Mode Amino-C18 columns from Dr. Maisch HPLC GmbH deliver versatile dual-mode separation capabilities – the ideal choice for complex mixture analysis and challenging HPLC applications.
Fully porous, ultra-pure silica with dual amino and C18 bonding
Mixed-mode retention: reversed-phase and polar interactions
Unique selectivity for complex or diverse analyte mixtures
High efficiency and reproducibility for both small molecules and polar compounds
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 3 µm and 5 µm particle sizes
Separation of mixtures containing polar and non-polar compounds
Pharmaceutical analysis of APIs and excipients in one run
Method development requiring orthogonal selectivity
Food, environmental, and natural product analysis
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | C18-NH2 |
| Particle Type | |
| Separation Modes | |
| USP Codes | |
| Endcapping | No |
| Carbonload | 17 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil Mixed-Mode Amino-C18, 3 µm | r13.18a. |
| ReproSil Mixed-Mode Amino-C18, 5 µm | r15.18a. |