Reprospher 120 SAX-C8 is a mixed-mode HPLC column combining strong anion exchange (SAX) functionality with hydrophobic C8 retention on spherical silica. This dual-mode interaction enables simultaneous ionic and hydrophobic selectivity, making the phase ideal for complex mixtures that contain both charged and nonpolar components. The column provides enhanced flexibility in method development by allowing fine-tuning of retention through pH, ionic strength, and organic modifier concentration. With its robust bonding chemistry and spherical silica base, Reprospher 120 SAX-C8 delivers reproducible separations, sharp peaks, and long column lifetimes.
Reprospher 120 SAX-C8 combines strong anion exchange with C8 retention – a powerful mixed-mode solution for challenging HPLC separations.
Mixed-mode stationary phase: strong anion exchange (SAX) + hydrophobic C8
Spherical silica with 120 Å pore size for high efficiency
Dual interaction mechanisms for charged and nonpolar analytes
Robust bonding chemistry ensures reproducibility and stability
Suitable for analytical and method development workflows
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 10 µm
Separation of acidic compounds and their nonpolar impurities
Pharmaceutical impurity profiling requiring dual selectivity
Biochemical analysis of anionic metabolites and peptides
Method development for complex mixtures with ionic and hydrophobic components
| Particle Size |
|
|---|---|
| Pore Size | 120 Å |
| Phase/Modification | C8-SAX |
| Particle Type | |
| Separation Modes | |
| USP Codes | |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher 120 SAX-C8, 10 µm | rs10.sax8. |