Reprospher Mixed-Mode Phenyl-C18 is a specialty HPLC column that combines a C18 alkyl chain with a phenyl functional group on spherical silica. This dual modification provides both hydrophobic retention and π–π interactions, offering complementary selectivity to conventional C18 or phenyl-only phases. The mixed-mode chemistry allows improved separation of structurally similar and aromatic analytes, while maintaining strong retention for hydrophobic compounds. The spherical silica ensures high mechanical stability, efficiency, and reproducibility across a wide range of applications.
Reprospher Mixed-Mode Phenyl-C18 combines hydrophobic and π–π selectivity – the versatile choice for laboratories facing complex separation challenges.
Mixed-mode stationary phase combining C18 and phenyl groups
Dual interaction mechanisms: hydrophobic retention + π–π selectivity
Enhanced resolution for aromatic and structurally related compounds
Spherical silica support for high efficiency and reproducibility
Suitable for analytical and method development workflows
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 5 µm and 10 µm particle sizes
Separation of aromatic pharmaceuticals and metabolites
Resolution of isomers and structurally related analytes
Biochemical and environmental analysis of aromatic compounds
Method development requiring complementary selectivity to standard C18
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Phase/Modification | C18-Phenyl |
| Particle Type | |
| Separation Mode | |
| USP Codes | |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Reprospher Mixed-Mode Phenyl-C18, 5 µm | rs15.9ph. |
| Reprospher Mixed-Mode Phenyl-C18, 10 µm | rs10.9ph. |