Platinum 300 C4 is a silica-based HPLC column with a butyl bonded phase on wide-pore (300 Å) silica, specifically engineered for the separation of peptides, proteins, and other biomacromolecules. The short C4 chains provide reduced hydrophobic retention compared to C18 or C8, allowing gentler interactions and faster elution of large biomolecules.
The wide-pore structure ensures excellent accessibility for high-molecular-weight analytes, delivering sharp peak shapes, reproducibility, and robustness. Platinum 300 C4 is particularly suitable for biopharmaceutical and proteomic applications requiring reliable separations of sensitive biomolecules.
Platinum 300 C4 provides reliable wide-pore performance with reduced hydrophobic interactions – the dependable choice for laboratories analyzing peptides and proteins in HPLC.
Wide-pore silica stationary phase with butyl (C4) bonded chemistry
Reduced hydrophobic retention for large biomolecules
Optimized for peptides, proteins, and macromolecular analysis
High reproducibility and robust column lifetime
Available particle sizes: 3 µm, 5 µm, 10 µm
Separation of peptides and small to medium-sized proteins
Biopharmaceutical testing of therapeutic proteins and biomolecules
Proteomic research requiring gentle retention of large analytes
Method development for biomolecular separations with reduced hydrophobicity
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Surface Area | 100 m²/g |
| Phase/Modification | C4 |
| Particle Type | |
| Separation Mode | |
| USP Code |
| Phase | Material Number |
|---|---|
| Platinum 300 C4, 3 µm | 5136688 |
| Platinum 300 C4, 5 µm | 5136689 |
| Platinum 300 C4, 10 µm | 5136703 |