Platinum 300 CN

Wide-Pore Cyano HPLC Column for Biomolecular and Polar Separations

Platinum 300 CN is a silica-based HPLC column with a cyano bonded phase on wide-pore (300 Å) silica, designed to provide unique selectivity for peptides, proteins, and polar biomolecules. The moderately polar cyano functionality combines hydrophobic and dipole–dipole interactions, making it a versatile alternative to C18 and C8 phases in biomolecular chromatography.

The wide-pore structure ensures accessibility for larger analytes, while the CN chemistry offers orthogonal selectivity compared to traditional alkyl phases. Platinum 300 CN is particularly suited for pharmaceutical, biochemical, and proteomic laboratories requiring complementary retention mechanisms.

Platinum 300 CN delivers versatile performance by combining wide-pore silica with polar cyano chemistry – the reliable choice for laboratories requiring complementary biomolecular separations.

Key Features:

  • Wide-pore silica stationary phase with cyano (CN) bonded chemistry

  • Combines polar and hydrophobic retention mechanisms

  • Optimized for peptides, proteins, and polar biomolecules

  • Provides orthogonal selectivity to C18 and C8 phases

  • Available particle size: 5 µm

Typical Applications:

  • Peptide and protein separations with complementary selectivity

  • Biochemical analysis of polar biomolecules and metabolites

  • Pharmaceutical impurity profiling with orthogonal retention mechanisms

  • Method development requiring alternative wide-pore selectivity

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 300 Å
Surface Area 100 m²/g
Phase/Modification CN
Particle Type
Separation Modes
USP Code

Material Number

Phase Material Number
Platinum 300 CN, 5 µm 6136986
Platinum 300 C18-EPS Platinum 300 Si

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