ReproShell C8

Core-Shell HPLC Column for Balanced Hydrophobic Retention

ReproShell C8 is a core-shell HPLC column with octyl bonded chemistry, offering medium hydrophobic retention and faster elution compared to C18 phases. This makes it particularly suitable for moderately hydrophobic analytes and for method development requiring complementary selectivity. The core-shell particle design delivers high efficiency, sharp peak shapes, and lower backpressure compared to fully porous particles. ReproShell C8 provides robust performance and reproducibility, making it a versatile choice for pharmaceutical, biochemical, food, and environmental laboratories.

ReproShell C8 combines the efficiency of core-shell technology with balanced hydrophobic retention – the reliable choice for laboratories requiring versatile HPLC separations.

Key Features:

  • Core-shell particle technology for high efficiency and reduced backpressure

  • Octyl bonded chemistry with medium hydrophobic retention

  • Faster elution compared to C18 phases, ideal for moderately hydrophobic analytes

  • High reproducibility and robust performance in routine and advanced separations

  • Available particle sizes: 2.7 µm, 5 µm

Typical Applications:

  • Pharmaceutical impurity profiling and stability testing

  • Biochemical separations of moderately hydrophobic drugs and metabolites

  • Food and beverage testing of additives and contaminants

  • Environmental monitoring of organic pollutants

  • Method development requiring complementary selectivity to C18

Specifications

Request Product
Particle Sizes
  • 2.7 µm
  • 5 µm
Pore Size 90 Å
Surface Area 140 m²/g
Phase/Modification C8
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 4 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproShell C8, 2.7 µm cs27.8e.
ReproShell C8, 5 µm cs15.8e.
ReproShell Biphenyl ReproShell C18

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