ReproShell PFP

Core-Shell Pentafluorophenyl HPLC Column for Polar and Aromatic Selectivity

ReproShell PFP is a core-shell HPLC column with pentafluorophenyl bonded chemistry, designed to provide unique selectivity for polar, aromatic, and halogenated compounds. The PFP functionality introduces π–π interactions, dipole–dipole forces, and hydrogen bonding, making it highly complementary to conventional C18 and C8 phases. The core-shell particle design ensures high efficiency, sharp peak shapes, and reduced backpressure, enabling faster and more reproducible separations without compromising resolution. ReproShell PFP is particularly suited for pharmaceutical, biochemical, and environmental laboratories requiring orthogonal selectivity.

ReproShell PFP combines the efficiency of core-shell technology with versatile PFP chemistry – the reliable choice for laboratories requiring high-performance polar and aromatic separations in HPLC.

Key Features:

  • Core-shell particle technology for high efficiency and reduced backpressure

  • Pentafluorophenyl (PFP) bonded chemistry with polar and aromatic selectivity

  • Multiple interaction mechanisms: π–π, dipole, and hydrogen bonding

  • High reproducibility and robust performance in routine and advanced analysis

  • Available particle sizes: 2.7 µm, 5 µm

Typical Applications:

  • Pharmaceutical impurity profiling with orthogonal selectivity to C18

  • Separation of aromatic and halogenated compounds

  • Biochemical analysis of polar metabolites and conjugated biomolecules

  • Environmental monitoring of pesticides and aromatic pollutants

  • Method development requiring enhanced polar and aromatic selectivity

Specifications

Request Product
Particle Sizes
  • 2.7 µm
  • 5 µm
Pore Size 90 Å
Surface Area 140 m²/g
Phase/Modification PFP
Particle Type
Separation Modes
USP Code
Endcapping Yes
Carbonload 4 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproShell PFP, 2.7 µm cs27.pfp.
ReproShell PFP, 5 µm cs15.pfp.
ReproShell ODS-3 ReproShell Phenyl-Hexyl

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info@dr-maisch.com +49 7073 5035 7

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