ReproShell Phenyl-Hexyl

Core-Shell HPLC Column with Dual Aromatic and Hydrophobic Selectivity

ReproShell Phenyl-Hexyl is a core-shell HPLC column with phenyl-hexyl bonded chemistry, combining π–π interactions from the phenyl ring with hydrophobic retention from the hexyl chain. This dual selectivity provides enhanced resolution for aromatic compounds while maintaining robust retention for moderately hydrophobic analytes. The core-shell particle design delivers high efficiency, sharp peak shapes, and reduced backpressure, allowing fast, reproducible separations with excellent resolution. ReproShell Phenyl-Hexyl is especially suited for pharmaceutical, biochemical, and environmental applications requiring complementary selectivity to standard C18 and C8 phases.

ReproShell Phenyl-Hexyl combines the efficiency of core-shell technology with dual aromatic and hydrophobic selectivity – the reliable choice for high-performance separations in pharmaceutical, biochemical, and environmental analysis.

Key Features:

  • Core-shell particle technology for high efficiency and reduced backpressure

  • Phenyl-hexyl bonded chemistry with dual aromatic and hydrophobic interactions

  • Enhanced π–π selectivity for aromatic analytes

  • High reproducibility and robust bonding for long column lifetimes

  • Available particle sizes: 2.7 µm, 5 µm

Typical Applications:

  • Pharmaceutical impurity profiling of aromatic and hydrophobic drugs

  • Biochemical analysis of aromatic amino acids and metabolites

  • Environmental monitoring of polycyclic aromatic hydrocarbons (PAHs)

  • Method development requiring orthogonal selectivity to C18 and C8 phases

Specifications

Request Product
Particle Sizes
  • 2.7 µm
  • 5 µm
Pore Size 90 Å
Surface Area 140 m²/g
Phase/Modification Phenyl-Hexyl
Particle Type
Separation Mode
USP Code
Endcapping No
Carbonload 5.5 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproShell Phenyl-Hexyl, 2.7 µm cs27.ph.
ReproShell Phenyl-Hexyl, 5 µm cs15.ph.
ReproShell PFP ReproShell Si

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info@dr-maisch.com +49 7073 5035 7

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