ReproShell Si

Core-Shell Silica HPLC Column for Normal-Phase Chromatography

ReproShell Si is an unbonded, high-purity silica HPLC column with core-shell particle technology, designed for normal-phase and adsorption chromatography. Its active silanol groups provide strong polar interactions, enabling reliable separation of nonpolar and weakly polar analytes not well retained on reversed-phase columns. The core-shell particle design ensures high efficiency, reduced backpressure, and sharp peak shapes, allowing faster and more reproducible normal-phase separations compared to fully porous silica. ReproShell Si is particularly suited for pharmaceutical, chemical, and environmental laboratories requiring robust and reproducible polar selectivity.

ReproShell Si combines the robustness of high-purity silica with the efficiency of core-shell technology – the dependable choice for laboratories performing normal-phase HPLC separations.

Key Features:

  • Core-shell particle technology for high efficiency and reduced backpressure

  • Unbonded high-purity silica with active silanol surface

  • Strong polar interactions for normal-phase chromatography

  • Robust and reproducible performance with sharp peak shapes

  • Available particle sizes: 2.7 µm, 5 µm

Typical Applications:

  • Normal-phase separations of nonpolar and weakly polar analytes

  • Pharmaceutical impurity profiling and stability testing

  • Chemical and petrochemical analysis requiring strong polar retention

  • Method development requiring orthogonal selectivity to reversed-phase phases

Specifications

Request Product
Particle Sizes
  • 2.7 µm
  • 5 µm
Pore Size 90 Å
Surface Area 140 m²/g
Phase/Modification Si
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 0 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproShell Si, 2.7 µm cs27.00.
ReproShell Si, 5 µm cs15.00.
ReproShell Phenyl-Hexyl

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info@dr-maisch.com +49 7073 5035 7

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