ReproSil Chiral-AMS-R

Amylose-Based Chiral Phase with (S)-α-Methylbenzyl Carbamate for Enantioselective Reversed-Phase Chromatography

ReproSil Chiral-AMS-R is a silica-based HPLC stationary phase coated with tris-(S)-α-methylbenzyl carbamate amylose, specifically developed for enantioselective separations under reversed-phase conditions. The chiral amylose derivative, substituted with (S)-α-methylbenzyl carbamate groups, provides a distinct stereochemical recognition pattern, enabling high enantioselectivity and resolution for a wide variety of chiral analytes.

Optimized for aqueous and polar mobile phases, ReproSil Chiral-AMS-R offers stable retention behavior, excellent reproducibility, and robust performance in gradient and isocratic operation. The phase is built on high-purity, mechanically stable spherical silica, ensuring long column lifetime and consistent results even under routine analytical conditions. With its combination of chiral selectivity and reversed-phase compatibility, ReproSil Chiral-AMS-R is ideally suited for pharmaceutical, biochemical, and academic laboratories focusing on chiral separations of polar and water-soluble compounds.

ReproSil Chiral-AMS-R combines the stereochemical selectivity of (S)-α-methylbenzyl carbamate amylose with reversed-phase compatibility – the reliable choice for precise and reproducible enantioselective separations in aqueous chromatographic systems.

Attractive alternative to CHIRALPAK® AS-RH (Daicel®).

For the use of our ReproSil Chiral-AMS-R columns, please refer to our Column Care Guide.

Key Features:

  • Silica-based stationary phase coated with tris-(S)-α-methylbenzyl carbamate amylose

  • Designed for enantioselective separations under reversed-phase conditions

  • Excellent chiral recognition and high resolution for diverse analytes

  • Stable and reproducible performance with aqueous and polar mobile phases

  • Suitable for analytical chiral HPLC applications

Typical Applications:

  • Enantioselective separation of chiral pharmaceuticals and intermediates

  • Analysis of polar and water-soluble chiral compounds

  • Quality control and purity testing of optically active substances

  • Method development and research in pharmaceutical and biochemical laboratories

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 1 000 Å
Surface Area 30 m²/g
Phase/Modification Tris-(S)-α-methylbenzylcarbamat-Amylose
Particle Type
Separation Modes
Endcapping No
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil Chiral-AMS-R, 3 µm r63.amsr.
ReproSil Chiral-AMS-R, 5 µm r65.amsr.
ReproSil Chiral-AMS ReproSil Chiral-Beta-CD

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info@dr-maisch.com +49 7073 5035 7

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