ReproSil Chiral-AMS-R is a silica-based HPLC stationary phase coated with tris-(S)-α-methylbenzyl carbamate amylose, specifically developed for enantioselective separations under reversed-phase conditions. The chiral amylose derivative, substituted with (S)-α-methylbenzyl carbamate groups, provides a distinct stereochemical recognition pattern, enabling high enantioselectivity and resolution for a wide variety of chiral analytes.
Optimized for aqueous and polar mobile phases, ReproSil Chiral-AMS-R offers stable retention behavior, excellent reproducibility, and robust performance in gradient and isocratic operation. The phase is built on high-purity, mechanically stable spherical silica, ensuring long column lifetime and consistent results even under routine analytical conditions. With its combination of chiral selectivity and reversed-phase compatibility, ReproSil Chiral-AMS-R is ideally suited for pharmaceutical, biochemical, and academic laboratories focusing on chiral separations of polar and water-soluble compounds.
ReproSil Chiral-AMS-R combines the stereochemical selectivity of (S)-α-methylbenzyl carbamate amylose with reversed-phase compatibility – the reliable choice for precise and reproducible enantioselective separations in aqueous chromatographic systems.
Attractive alternative to CHIRALPAK® AS-RH (Daicel®).
For the use of our ReproSil Chiral-AMS-R columns, please refer to our Column Care Guide.
Silica-based stationary phase coated with tris-(S)-α-methylbenzyl carbamate amylose
Designed for enantioselective separations under reversed-phase conditions
Excellent chiral recognition and high resolution for diverse analytes
Stable and reproducible performance with aqueous and polar mobile phases
Suitable for analytical chiral HPLC applications
Enantioselective separation of chiral pharmaceuticals and intermediates
Analysis of polar and water-soluble chiral compounds
Quality control and purity testing of optically active substances
Method development and research in pharmaceutical and biochemical laboratories
| Particle Sizes |
|
|---|---|
| Pore Size | 1 000 Å |
| Surface Area | 30 m²/g |
| Phase/Modification | Tris-(S)-α-methylbenzylcarbamat-Amylose |
| Particle Type | |
| Separation Modes | |
| Endcapping | No |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil Chiral-AMS-R, 3 µm | r63.amsr. |
| ReproSil Chiral-AMS-R, 5 µm | r65.amsr. |