ReproSil DIBS-C4 is a silica-based HPLC column with a butyl bonded phase developed for the Direct Injection of Biological Samples (DIBS). The C4 modification provides moderate hydrophobic retention, making it particularly well-suited for the separation of proteins, peptides, and other biomolecules from complex biological matrices. The specialized DIBS surface chemistry minimizes secondary interactions and adsorption of biomolecules, allowing reliable direct injection of plasma, serum, or other biological fluids without extensive sample preparation. With its robust silica backbone and optimized surface properties, ReproSil DIBS-C4 ensures reproducible results, sharp peak shapes, and long column lifetimes.
ReproSil DIBS-C4 combines the robustness of silica with tailored C4 modification – the reliable solution for reproducible and efficient direct injection bioanalysis.
Silica-based stationary phase with C4 modification for DIBS applications
Optimized for proteins, peptides, and other biomolecules
Enables direct injection of biological fluids with minimal sample prep
Reduced secondary interactions for improved reproducibility
Robust silica matrix ensures mechanical and chemical stability
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 20 µm particle size
Bioanalysis of proteins and peptides from biological fluids
Direct HPLC injection of plasma, serum, and other matrices
Pharmaceutical and clinical research involving biomolecules
Method development for complex biological samples
| Particle Size |
|
|---|---|
| Pore Size | 120 Å |
| Surface Area | 220 m²/g |
| Phase/Modification | C4 |
| Particle Type | |
| Separation Modes | |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil DIBS-C4, 20 µm | dibs20.40. |