ReproSil DIBS-C8

Silica Phase with C8 Modification for Direct Injection of Biological Samples

ReproSil DIBS-C8 is a high-purity silica-based HPLC column featuring an octyl bonded phase designed for the Direct Injection of Biological Samples (DIBS). The medium-chain C8 modification provides a balanced hydrophobic retention that is ideal for peptides, proteins, and metabolites in complex biological matrices. The DIBS-specific surface treatment reduces non-specific adsorption and suppresses unwanted matrix effects, enabling reliable direct injection of serum, plasma, and other biological fluids. With its robust silica support and optimized bonding chemistry, ReproSil DIBS-C8 ensures consistent performance, sharp peak shapes, and excellent reproducibility across demanding bioanalytical applications.

ReproSil DIBS-C8 combines medium hydrophobic selectivity with DIBS technology – the dependable choice for direct bioanalysis of complex samples.

Key Features:

  • Silica-based stationary phase with octyl (C8) bonding for DIBS

  • Balanced hydrophobic retention for peptides, proteins, and metabolites

  • Minimizes adsorption and matrix effects in biological samples

  • Enables direct injection without extensive sample preparation

  • High robustness and reproducibility for routine and advanced use

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 20 µm particle size

Typical Applications:

  • Direct HPLC analysis of peptides, proteins, and metabolites

  • Injection of plasma, serum, and other biological matrices

  • Bioanalytical method development and validation

  • Pharmaceutical and clinical research requiring reproducible separations

Specifications

Request Product
Particle Size
  • 20 µm
Pore Size 120 Å
Phase/Modification C8
Particle Type
Separation Modes
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil DIBS-C8, 20 µm dibs20.80.
ReproSil DIBS-C4 ReproSil DIBS-C18

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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