ReproSil DIBS-RP-C4

Sterically Protected C4 Column for Stable and Gentle Biomolecule Separations

ReproSil DIBS-RP-C4 from Dr. Maisch HPLC GmbH is a fully porous, high-purity silica HPLC column with a sterically protected butyl (C4) bonded phase based on diisobutylsilane (DIBS) chemistry. The short alkyl chain provides reduced hydrophobic retention, enabling gentle elution of sensitive biomolecules such as proteins, peptides, and glycoproteins, while the steric protection ensures excellent phase stability under a wide pH range.

This combination results in extended column lifetime, minimal ligand loss, and consistent performance in demanding analytical environments.

ReproSil DIBS-RP-C4 columns from Dr. Maisch HPLC GmbH deliver gentle, reproducible wide-pore separations with outstanding stability – the optimal choice for sensitive protein and biomolecule HPLC applications.

Key Features:

  • Fully porous, ultra-pure silica with sterically protected C4 bonding

  • DIBS chemistry for improved stability at extreme pH values

  • Gentle hydrophobic retention for large biomolecules

  • Enhanced durability and reproducibility for long-term use

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Protein and peptide separations under mild conditions

  • Biopharmaceutical QC and characterization

  • High-pH or low-pH reversed-phase biomolecule analysis

  • Method development for large, sensitive analytes

Specifications

Request Product
Particle Size
  • 10 µm
Pore Size 120 Å
Particle Type
Separation Modes
USP Code
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil DIBS-RP-C4, 10 µm r10.dibs.
ReproSil DIBS-RP

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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