ReproSil DIBS-RP

Reversed-Phase Silica for Direct Injection of Biological Samples

ReproSil DIBS-RP is a silica-based HPLC column with a reversed-phase bonded surface, specially developed for the Direct Injection of Biological Samples (DIBS). Its balanced reversed-phase chemistry ensures broad applicability, providing reliable retention for a wide range of biomolecules, from small metabolites to peptides and proteins. The dedicated DIBS surface treatment reduces non-specific adsorption and minimizes matrix effects, allowing direct analysis of complex biological samples such as plasma, serum, or cell culture media without extensive sample preparation. ReproSil DIBS-RP offers robust performance, reproducibility, and long column lifetimes, making it a versatile solution for bioanalytical workflows.

ReproSil DIBS-RP combines universal reversed-phase selectivity with specialized DIBS technology – the dependable choice for efficient and reproducible direct injection of biological samples.

Key Features:

  • Silica-based stationary phase with reversed-phase bonding for DIBS

  • Broad selectivity suitable for metabolites, peptides, and proteins

  • Optimized for direct injection of biological fluids without sample prep

  • Reduced matrix interferences and non-specific adsorption

  • Robust and reproducible performance for demanding applications

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm particle size

Typical Applications:

  • Direct injection analysis of plasma, serum, and other biological fluids

  • Bioanalytical HPLC of metabolites, peptides, and proteins

  • Pharmaceutical and clinical studies requiring routine reproducibility

  • Method development for complex biological matrices

Specifications

Request Product
Particle Size
  • 5 µm
Pore Size 120 Å
Surface Area 220 m²/g
Particle Type
Separation Mode
Carbonload 15.5 %
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil DIBS-RP, 5 µm r15.dibs.
ReproSil DIBS-C18 ReproSil DIBS-RP-C4

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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