ReproSil Gold 200 C4

Wide-Pore C4 Column for Gentle Protein and Biomolecule Separations

ReproSil Gold 200 C4 from Dr. Maisch HPLC GmbH is a high-purity silica HPLC column with a 200 Å pore size and a butyl bonded phase. The short alkyl chain provides reduced hydrophobic retention, enabling mild elution conditions that help preserve the structural integrity and biological activity of large proteins, enzymes, and biomolecules. The extra-wide pore size ensures optimal accessibility and mass transfer for high-molecular-weight analytes, while delivering sharp peak shapes, high resolution, and excellent reproducibility.

ReproSil Gold 200 C4 columns from Dr. Maisch HPLC GmbH deliver gentle, reproducible separations with wide-pore accessibility – the preferred choice for sensitive protein and biomolecule HPLC applications.

Key Features:

  • Fully porous, ultra-pure silica with 200 Å pore size

  • C4 bonding – USP L26 classification

  • Gentle hydrophobic retention for sensitive biomolecules

  • Optimized for large proteins, enzymes, and biomolecules

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 3 µm, 5 µm, and 10 µm particle sizes

Typical Applications:

  • Protein and enzyme separations under mild conditions

  • Biopharmaceutical QC and proteomics research

  • Gradient HPLC for large, hydrophobic biomolecules

  • Method development for labile analytes

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 200 Å
Surface Area 200 m²/g
Phase/Modification C4
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 5 %
pH Range 2 to 9

Material Numbers

Phase Material Number
ReproSil Gold 200 C4, 3 µm r23.4g.
ReproSil Gold 200 C4, 5 µm r25.4g.
ReproSil Gold 200 C4, 10 µm r20.4g.
ReproSil Gold 200 C8

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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