ReproSil Gold 200 C8

Wide-Pore C8 Column for Balanced Retention of Large Biomolecules

ReproSil Gold 200 C8 from Dr. Maisch HPLC GmbH is a high-purity silica HPLC column with a 200 Å pore size and an octyl bonded phase. This medium-chain phase provides moderate hydrophobic retention, enabling faster elution than C18 while still offering excellent resolution for large biomolecules such as proteins, enzymes, and glycoproteins. The extra-wide pore structure ensures efficient mass transfer and optimal accessibility for high-molecular-weight analytes, while delivering sharp peaks, high resolution, and reproducible retention.

ReproSil Gold 200 C8 columns from Dr. Maisch HPLC GmbH combine balanced retention with wide-pore accessibility – the versatile choice for large biomolecule chromatography in HPLC.

Key Features:

  • Fully porous, ultra-pure silica with 200 Å pore size

  • C8 bonding – USP L7 classification

  • Balanced hydrophobic retention for faster separations than C18

  • Optimized for proteins, enzymes, and large biomolecules

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 3 µm, 5 µm, and 10 µm particle sizes

Typical Applications:

  • Protein and peptide separations in proteomics and biopharma

  • Biopharmaceutical quality control and characterization

  • Gradient HPLC of large and hydrophobic biomolecules

  • Method development requiring moderate retention

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 200 Å
Surface Area 200 m²/g
Phase/Modification C8
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 8 %
pH Range 2 to 9

Material Numbers

Phase Material Number
ReproSil Gold 200 C8, 3 µm r23.8g.
ReproSil Gold 200 C8, 5 µm r25.8g.
ReproSil Gold 200 C8, 10 µm r20.8g.
ReproSil Gold 200 C4 ReproSil Gold 200 C18

Any questions?
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info@dr-maisch.com +49 7073 5035 7

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