ReproSil Gold 300 C2

Wide-Pore C2 Column for Minimal Hydrophobic Retention in Large Biomolecule Analysis

ReproSil Gold 300 C2 from Dr. Maisch HPLC GmbH is a high-purity silica HPLC column with a 300 Å pore size and an dimethyl bonded phase. The very short alkyl chain provides minimal hydrophobic retention, making it ideal for fast elution of highly hydrophobic large biomolecules and for applications where reduced interaction with the stationary phase is desired. The extra-wide pore structure ensures excellent accessibility and efficient mass transfer for proteins, enzymes, and glycoproteins, while maintaining sharp peak shapes and high reproducibility.

ReproSil Gold 300 C2 columns from Dr. Maisch HPLC GmbH deliver minimal hydrophobicity with wide-pore accessibility – the ideal choice for specialized large biomolecule HPLC separations.

Key Features:

  • Fully porous, ultra-pure silica with 300 Å pore size

  • C2 bonding for minimal hydrophobic retention

  • Optimized for fast elution of hydrophobic biomolecules

  • Suitable for proteins, enzymes, and other large molecules

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 5 µm and 10 µm particle sizes

Typical Applications:

  • Fast gradient separations of hydrophobic proteins and peptides

  • Method development for low-retention biomolecule chromatography

  • Biopharmaceutical QC requiring minimal stationary-phase interaction

  • Specialized separations of high-molecular-weight analytes

Specifications

Request Product
Particle Sizes
  • 5 µm
  • 10 µm
Pore Size 300 Å
Surface Area 100 m²/g
Phase/Modification C2
Particle Type
Separation Mode
USP Codes
Endcapping Yes
Carbonload 1 %
pH Range 2 to 9

Material Numbers

Phase Material Number
ReproSil Gold 300 C2, 5 µm r35.2g.
ReproSil Gold 300 C2, 10 µm r30.2g.
ReproSil Gold 300 C4

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us