ReproSil-Pur 120 C1

Short-Chain Alkyl HPLC Column for Fast and Polar-Selective Separations

ReproSil-Pur 120 C1 is a silica-based HPLC column with a methyl bonded phase on high-purity 120 Å silica. Its short-chain alkyl functionality provides minimal hydrophobic retention compared to longer-chain alkyl phases (C8, C18), resulting in faster elution and increased selectivity for polar compounds.

With sharp peak shapes, reproducibility, and robust bonding chemistry, ReproSil-Pur 120 C1 is a reliable option for pharmaceutical, biochemical, and environmental applications requiring complementary selectivity to conventional reversed-phase columns.

ReproSil-Pur 120 C1 provides minimal hydrophobic retention with robust silica performance – the dependable choice for laboratories requiring polar-selective HPLC separations.

Key Features:

  • High-purity silica with methyl (C1) bonded chemistry

  • 120 Å pore size optimized for small to medium-sized molecules

  • Minimal hydrophobic retention for faster elution of analytes

  • Excellent reproducibility with sharp peak symmetry

  • Robust bonding ensures long column lifetime

  • Available particle sizes: 3 µm, 5 µm

Typical Applications:

  • Pharmaceutical impurity profiling with complementary selectivity to C18

  • Biochemical separations of polar drugs, metabolites, and small biomolecules

  • Food and beverage analysis of polar additives and contaminants

  • Environmental monitoring of polar organic compounds

  • Method development requiring fast separations and orthogonal selectivity

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 120 Å
Surface Area 300 m²/g
Phase/Modification C1
Particle Type
Separation Mode
USP Code
Endcapping Yes
Carbonload 4 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil-Pur 120 C1, 3 µm r13.1e.
ReproSil-Pur 120 C1, 5 µm r15.1e.
ReproSil-Pur 120 C4

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