ReproSil-Pur 120 Diol is a silica-based HPLC column with bonded diol functionality on high-purity 120 Å silica. The diol surface provides controlled hydrophilicity, making the column highly suitable for hydrophilic interaction chromatography (HILIC) as well as size-based separations of small molecules.
Compared to bare silica, the bonded diol layer reduces strong silanol interactions while maintaining polar selectivity, resulting in improved reproducibility and peak symmetry. This makes ReproSil-Pur 120 Diol an excellent tool for pharmaceutical, biochemical, food, and environmental laboratories working with polar analytes.
ReproSil-Pur 120 Diol delivers reliable polar selectivity with improved reproducibility – the versatile choice for laboratories requiring HILIC and normal-phase HPLC separations.
High-purity silica with bonded diol functionality
120 Å pore size optimized for small to medium-sized molecules
Suitable for HILIC and normal-phase applications
Reduced silanol activity compared to bare silica for better peak shapes
Available particle sizes: 3 µm, 5 µm, 10 µm
Pharmaceutical analysis of hydrophilic drugs and metabolites
Biochemical testing of sugars, nucleosides, and polar compounds
Food and beverage analysis of carbohydrates and organic acids
Environmental monitoring of polar pollutants
Method development requiring hydrophilic interaction separations
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Surface Area | 300 m²/g |
| Phase/Modification | Diol |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | No |
| Carbonload | 7 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil-Pur 120 Diol, 3 µm | r13.d0. |
| ReproSil-Pur 120 Diol, 5 µm | r15.d0. |
| ReproSil-Pur 120 Diol, 10 µm | r10.d0. |