ReproSil-Pur 120 CN is a silica-based HPLC column with bonded cyano functionality on high-purity 120 Å silica. The moderately polar stationary phase provides unique selectivity through dipole–dipole and weak hydrophobic interactions, making it highly complementary to traditional alkyl phases such as C18 and C8.
Its versatility allows operation in both reversed-phase and normal-phase modes, offering broad applicability for pharmaceutical, biochemical, food, and environmental laboratories. The robust bonding chemistry ensures reproducibility, sharp peak shapes, and long column lifetimes.
ReproSil-Pur 120 CN provides flexible operation and complementary selectivity – the dependable choice for laboratories requiring polar-interaction chromatography in HPLC.
High-purity silica with cyano (CN) bonded chemistry
120 Å pore size optimized for small to medium-sized molecules
Dual functionality for reversed-phase and normal-phase operation
Polar selectivity with dipole–dipole and weak hydrophobic interactions
Available particle sizes: 3 µm, 5 µm, 10 µm
Pharmaceutical analysis of polar and moderately hydrophobic drugs
Biochemical separations of metabolites and small biomolecules
Food and beverage testing for additives and polar residues
Environmental monitoring of pesticides and organic pollutants
Method development requiring orthogonal selectivity to C18 and C8 phases
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Surface Area | 300 m²/g |
| Phase/Modification | CN |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 7 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil-Pur 120 CN, 3 µm | r13.ce. |
| ReproSil-Pur 120 CN, 5 µm | r15.ce. |
| ReproSil-Pur 120 CN, 10 µm | r10.ce. |