ReproSil-Pur 200 C18-AQ is a silica-based HPLC column with octadecyl bonded chemistry on high-purity 200 Å silica, modified for full aqueous stability. Unlike conventional C18 phases, the AQ modification prevents phase collapse under 100% aqueous mobile phases, making it highly suitable for the retention of polar analytes and peptides.
The wide-pore structure ensures excellent accessibility for biomolecules such as peptides and small proteins, while the robust bonding chemistry guarantees reproducibility and long operational lifetimes. This makes ReproSil-Pur 200 C18-AQ an excellent choice for biopharmaceutical, biochemical, and pharmaceutical laboratories.
ReproSil-Pur 200 C18-AQ provides wide-pore accessibility with full aqueous stability – the dependable choice for laboratories analyzing peptides and polar analytes by HPLC.
High-purity silica with octadecyl (C18) bonded chemistry and AQ modification
200 Å pore size optimized for peptides and small proteins
Stable in 100% aqueous mobile phases – no phase collapse
Strong hydrophobic retention combined with enhanced polar selectivity
Available particle sizes: 1.9 µm - 50 µm
Peptide mapping and biopharmaceutical analysis
Separation of polar drugs and hydrophilic metabolites
Biochemical analysis of peptides, small proteins, and polar biomolecules
Food and beverage testing of hydrophilic compounds
Method development requiring aqueous-compatible reversed-phase selectivity
| Particle Sizes |
|
|---|---|
| Pore Size | 200 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Modes | |
| USP Codes | |
| Endcapping | Yes |
| Carbonload | 11 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil-Pur 200 C18-AQ, 1.9 µm | r219.aq. |
| ReproSil-Pur 200 C18-AQ, 3 µm | r23.aq. |
| ReproSil-Pur 200 C18-AQ, 5 µm | r25.aq. |
| ReproSil-Pur 200 C18-AQ, 10 µm | r20.aq. |
| ReproSil-Pur 200 C18-AQ, 50 µm | r50.aq. |