ReproSil-Pur Basic 100 Si

High-Purity Silica Column for Normal-Phase Separations

ReproSil-Pur Basic 100 Si is an unbonded, high-purity silica HPLC column with a 100 Å pore size, designed for normal-phase and adsorption chromatography. The active silanol groups provide strong polar interactions, making this column well suited for analytes that are insufficiently retained on reversed-phase phases.

With its optimized surface and high-purity silica, ReproSil-Pur Basic 100 Si delivers sharp peak shapes, reproducibility, and robust performance in pharmaceutical, biochemical, and environmental applications.

ReproSil-Pur Basic 100 Si provides high-purity silica performance with strong polar selectivity – the reliable choice for laboratories performing normal-phase HPLC separations of small molecules.

Key Features:

  • Unbonded, high-purity silica stationary phase

  • 100 Å pore size optimized for small molecule separations

  • Strong polar interactions for normal-phase chromatography

  • Excellent reproducibility and sharp peak symmetry

  • Available particle sizes: 3 µm, 5 µm

Typical Applications:

  • Normal-phase separations of nonpolar and weakly polar compounds

  • Pharmaceutical impurity profiling and stability testing

  • Biochemical analysis requiring polar selectivity

  • Environmental monitoring of nonpolar pollutants

  • Method development requiring orthogonal selectivity to reversed-phase HPLC

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
Pore Size 100 Å
Surface Area 450 m²/g
Phase/Modification Si
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 0 %
pH Range 2 to 8

Material Numbers

Phase Material Number
ReproSil-Pur Basic 100 Si, 3 µm r13.b0.
ReproSil-Pur Basic 100 Si, 5 µm r15.b0.
ReproSil-Pur Basic C5

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us