ReproSil-Pur Basic C5 is a silica-based HPLC column with pentyl bonded chemistry on high-purity silica. With shorter alkyl chains than C8 or C18, it provides moderate hydrophobic retention and faster elution, making it particularly suitable for analytes requiring reduced retention times or complementary selectivity in method development.
As part of the ReproSil-Pur Basic series, the column is specially optimized for basic and polar compounds. Reduced silanol activity ensures sharp peak shapes and improved reproducibility, especially for amines, alkaloids, and pharmaceuticals prone to peak tailing on conventional phases.
ReproSil-Pur Basic C5 provides balanced hydrophobic retention with optimized selectivity for basic analytes – the reliable choice for laboratories requiring robust reversed-phase HPLC separations.
High-purity silica with pentyl (C5) bonded chemistry
Optimized for basic and polar analytes with reduced silanol interactions
Moderate hydrophobic retention, faster elution than C8/C18 phases
Excellent reproducibility and peak symmetry
Available particle size: 10 µm
Pharmaceutical analysis of basic drugs, alkaloids, and amines
Biochemical separations of polar metabolites and small biomolecules
Food and beverage testing of nitrogen-containing compounds
Environmental monitoring of cationic pollutants
Method development requiring complementary selectivity to C8 and C18
| Particle Size |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 450 m²/g |
| Phase/Modification | C5 |
| Particle Type | |
| Separation Mode | |
| Endcapping | Yes |
| Carbonload | 12.5 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil-Pur Basic C5, 10 µm | r10.b5. |