ReproSil Saphir 1000 Si

Extra-Wide-Pore Unmodified Silica Column for Large Biomolecule Chromatography

ReproSil Saphir 1000 Si from Dr. Maisch HPLC GmbH is a high-purity, fully porous silica HPLC column with an extra-wide 1000 Å pore size, designed for the separation of very large biomolecules and macromolecular complexes. Without any bonded phase modification, the unmodified silica surface provides highly polar interaction properties, making it suitable for normal-phase chromatography and specific bioanalytical applications. The extremely large pores allow optimal accessibility and efficient mass transfer for analytes such as monoclonal antibodies, protein complexes, viruses, and nanoparticles.

ReproSil Saphir 1000 Si columns from Dr. Maisch HPLC GmbH deliver exceptional accessibility and polar surface selectivity – the ideal choice for very large biomolecule and specialized normal-phase HPLC applications.

Key Features:

  • Fully porous, ultra-pure unmodified silica with 1000 Å pore size

  • Ideal for very large biomolecules and macromolecular assemblies

  • Suitable for normal-phase and specialized bioanalytical applications

  • Excellent mass transfer and accessibility for high-MW analytes

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

  • Available in 10 µm

Typical Applications:

  • Size-based separations of large biomolecules

  • Analysis of monoclonal antibodies (mAbs) and protein complexes

  • Normal-phase chromatography of polar large-molecule analytes

  • Biopharmaceutical QC and preparative purification

Specifications

Request Product
Particle Size
  • 10 µm
Pore Size 1 000 Å
Surface Area 30 m²/g
Phase/Modification Si
Particle Type
Separation Mode
Endcapping No
Carbonload 0 %
pH Range 2 to 8

Material Number

Phase Material Number
ReproSil Saphir 1000 Si, 10 µm ra60.00
ReproSil Saphir 1000 C18-2 HE

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us