ReproSil Saphir 300 SCX from Dr. Maisch HPLC GmbH is a high-purity silica-based HPLC column with a 300 Å wide-pore structure and a strong cation exchange bonded phase based on sulfonic acid functional groups. This phase provides strong ionic retention for positively charged analytes, delivering high resolution, sharp peak shapes, and reproducible retention times. The wide-pore design ensures optimal accessibility and efficient mass transfer for high-molecular-weight analytes such as proteins, enzymes, and peptides, making it particularly suitable for biopharmaceutical and proteomics applications.
ReproSil Saphir 300 SCX columns from Dr. Maisch HPLC GmbH combine wide-pore accessibility with strong ionic selectivity – the optimal choice for high-resolution large biomolecule chromatography.
Fully porous, ultra-pure silica with 300 Å pore size
Strong cation exchange (SCX) phase with sulfonic acid groups
High selectivity for basic biomolecules and peptides
Excellent reproducibility, resolution, and peak symmetry
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Available in 5 µm, 10 µm, and 15 µm particle sizes
Protein and peptide separations via strong cation exchange
Biopharmaceutical QC and charge variant analysis
Fractionation of protein isoforms in proteomics
Preparative purification of basic biomolecules
| Particle Sizes |
|
|---|---|
| Pore Size | 300 Å |
| Surface Area | 100 m²/g |
| Phase/Modification | SCX |
| Particle Type | |
| Separation Mode | |
| USP Codes | |
| Endcapping | No |
| Carbonload | 6 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| ReproSil Saphir 300 SCX, 5 µm | ra35.scx. |
| ReproSil Saphir 300 SCX, 10 µm | ra30.scx. |
| ReproSil Saphir 300 SCX, 15 µm | ra315.scx. |